Human GBP4 ELISA Kit (HUFI04152)

Quantify Guanylate Binding Protein 4 (GBP4) in human samples with this dedicated ELISA kit from Assay Genie. GBP4 belongs to the interferon-inducible guanylate-binding protein family, a group of dynamin-related GTPases that participate in cell-autonomous immunity. Its expression is strongly upregulated by interferon-gamma and type I interferons, and the protein contributes to host defense against intracellular bacteria and parasites by promoting the lysis of pathogen-containing vacuoles and supporting inflammasome activation.

This kit supports research into the interferon response, innate immunity, and inflammatory signaling, making it a useful tool for studies of infectious disease, autoimmune conditions, and the tumor microenvironment where GBP family members influence cytotoxic lymphocyte activity. Each kit supplies reagents sufficient for 96 assays in a microplate-based format and is intended for research use only.

Investigators studying viral restriction, antimicrobial defense mechanisms, and cytokine-driven immune regulation can use GBP4 as a marker of type II interferon pathway activation. Pair measurements of GBP4 with related readouts such as GBP1, GBP2, or GBP5 to capture broader patterns of innate immune engagement, and follow the included protocol with standard laboratory controls to ensure reproducible results.