Human GATAD2B ELISA Kit (HUFI07873)

The GATAD2B gene encodes a subunit of the NuRD (Nucleosome Remodeling and Deacetylase) chromatin-remodeling complex, which is increasingly studied for its role in transcriptional repression, histone deacetylation, and neural development. Loss-of-function variants in GATAD2B have been linked to a syndromic intellectual disability characterized by childhood-onset speech delay, hypotonia, and dysmorphic features, making quantitative measurement of the encoded protein valuable for neuroscience and developmental-biology workflows.

Researchers investigating NuRD complex composition, chromatin regulation in cancer cell lines, or biomarkers associated with neurodevelopmental disorders can use this kit from Assay Genie to specifically quantify human GATAD2B levels in clinical specimens through a microplate-based assay workflow. Each kit contains reagents sufficient for 96 individual determinations, with components stored refrigerated at 4 degrees C until first use to preserve antibody binding activity. The captured protein is detected with a labeled secondary antibody and a chromogenic substrate, with absorbance read on a standard plate reader for quantitative analysis intended for research use only.