Human GAN ELISA Kit (HUFI04185)

The Assay Genie GAN ELISA Kit supports quantitative measurement of gigaxonin, the protein encoded by the GAN gene, for research use only. Gigaxonin is a BTB-Kelch domain adaptor for an E3 ubiquitin ligase complex, and its dysfunction is associated with Giant Axonal Neuropathy, a rare progressive disorder of the peripheral and central nervous systems that disrupts intermediate filament organization in neurons.

Researchers investigating cytoskeletal regulation, ubiquitin-proteasome biology, and neurodegenerative disease mechanisms can use this in vitro assay to quantify gigaxonin in human biofluid specimens. Each kit includes a pre-coated microplate, matched antibody pairs, recombinant standards, and substrate buffer sufficient for a full plate run, with all reagents validated for absorbance-based readout.

For best results, store unopened kit components refrigerated at 4 degrees C, protect the chromogenic substrate from light, and avoid repeated freeze-thaw cycles of any aliquoted reagents. Allow all materials to equilibrate to room temperature before initiating the assay, and follow the enclosed protocol for standards, samples, and incubation timing.