Human GABARAPL1 (Gamma-aminobutyric acid receptor-associated protein-like 1) ELISA Kit (HUFI07882)

GABARAPL1 is an ATG8-family ubiquitin-like modifier that anchors to autophagosomal membranes during macroautophagy. Although it shares sequence homology with GABA-A receptor-associated protein, GABARAPL1 does not bind GABA; instead, it drives cargo recruitment, mitophagy, and intracellular vesicle trafficking. Altered GABARAPL1 expression has been reported in hepatocellular carcinoma, clear cell renal carcinoma, Alzheimer's disease brain tissue, and during osteoclastogenesis, positioning the protein as a marker of interest in cancer research, neurobiology, and metabolic disease studies.

This quantitative immunoassay from Assay Genie is configured to measure GABARAPL1 in human samples using an absorbance-based readout. The kit is supplied as a 96 Assays microplate format with all reagents required to generate a standard curve and quantify unknown specimens. Researchers commonly apply it to monitor autophagic activity in response to nutrient stress, evaluate biomarker changes in tumor versus matched normal tissue, and probe cross-talk between autophagy and apoptosis pathways.

The workflow follows standard ELISA principles: dispense sample, incubate, wash, add detection reagent, and read absorbance. Reagents are intended for research use only and should be refrigerated upon arrival; long-term storage of diluted working solutions is not recommended. Each Assay Genie GABARAPL1 ELISA Kit ships with a precoated plate, lyophilized standards, biotinylated detection antibody, streptavidin-HRP conjugate, substrate, and stop solution sufficient for the full plate.