Human G6PC3 ELISA Kit (HUFI04211)

Glucose-6-Phosphatase Catalytic Subunit 3 (G6PC3) is an endoplasmic reticulum membrane protein that hydrolyzes glucose-6-phosphate to glucose and inorganic phosphate, reactions supporting gluconeogenesis and neutrophil survival. Loss-of-function mutations in G6PC3 cause severe congenital neutropenia type 4 (SCN4), and altered expression has been documented in inflammatory bowel disease, candidiasis susceptibility, and ER-stress-related hematopoietic disorders. Researchers rely on this human-specific quantitative immunoassay from Assay Genie to measure G6PC3 protein levels in blood-derived specimens, supporting investigations into neutrophil biology, primary immunodeficiency, and metabolic dysfunction. The microplate-based kit provides pre-coated wells and detection reagents for routine bench workflow, with refrigeration between runs recommended. For research use only; not for diagnostic applications.