Human G3BP1 ELISA Kit (HUFI04210)

Pivotal in stress granule nucleation and mRNA translation control, G3BP1 (Ras-GTPase-activating protein SH3-domain-binding protein 1) is an RNA-binding protein central to cellular stress response research. This Assay Genie kit provides quantitative measurement of human G3BP1, supporting investigations into stress granule biology, Ras signaling crosstalk, and post-transcriptional gene regulation. The 96 Assays format offers throughput suited to cohort-scale studies, while compatibility with standard microplate instrumentation enables straightforward integration into existing laboratory workflows.

Each kit includes reagents for in vitro assays against human samples, with applications spanning cancer biology research, viral-host interaction studies, and innate immune signaling. The well-characterized S6K1-mediated phosphorylation at Ser219, which gates G3BP1 activity during stress granule assembly, makes this protein a focal point for studies on translational control and RNA metabolism. Researchers probing tumor microenvironment remodeling, neurodegeneration, and cytoplasmic mRNP remodeling will find this ELISA kit a useful reagent for dissecting stress-induced signaling cascades and biomarker discovery efforts.