Human Frizzled 2 ELISA Kit (HUFI07884)

Quantitative measurement of Frizzled 2, a seven-transmembrane G-protein coupled receptor central to Wnt/β-catenin and non-canonical Wnt signaling cascades, is supported by the Human Frizzled 2 ELISA Kit from Assay Genie, serving cancer biology, developmental research, and stem cell investigations.

Frizzled 2 partners with LRP5/6 co-receptors in canonical Wnt signaling and couples to Dishevelled and heterotrimeric G proteins in planar cell polarity pathways. Altered FZD2 expression has been linked to tumor progression and epithelial-mesenchymal transition in several cancer models, positioning the receptor as a focus of biomarker discovery and signal transduction research.

Each kit ships as a complete reagent set including pre-coated plates, capture antibody, detection reagent, standards, and buffer solutions supplied in vial and bottle formats. The kit is intended for research use only and is compatible with standard plate readers.

The assay supports cell culture supernatant analysis, tissue lysate characterization, and recombinant protein quantification workflows. Application areas include PCR-adjacent validation studies, flow cytometry cross-confirmation, and chromatography-based downstream analysis when paired with additional analytical methods.