Human FOXRED1 ELISA Kit (HUFI04250)

The Human FOXRED1 ELISA Kit from Assay Genie enables quantitative measurement of FAD-Dependent Oxidoreductase Domain Containing 1 (FOXRED1) in human research samples. FOXRED1 encodes a mitochondrial inner membrane protein of approximately 242 amino acids that participates in the assembly pathway of respiratory chain Complex I (NADH:ubiquitin oxidoreductase). Loss-of-function variants in FOXRED1 have been identified in patients with autosomal recessive mitochondrial complex I deficiency (MC1DN17), early-onset Leigh syndrome, and other oxidative phosphorylation disorders, supporting the value of quantitative FOXRED1 measurement in mitochondrial biogenesis research and inherited metabolic disease studies.

The microplate immunoassay includes all necessary reagents and is intended for research use only in laboratory settings. Investigators can apply this kit to characterize FOXRED1 expression across patient-derived fibroblasts, lymphoblast cell lines, and tissue homogenates, supporting research into mitochondrial pathophysiology, biomarker discovery, and potential therapeutic targets for mitochondrial disease.