Human Folate Receptor 2, Adult (FOLR2) ELISA Kit

Researchers studying tumor-associated macrophages, folate metabolism, and FRβ-targeted drug delivery rely on quantitative measurement of Folate Receptor 2 (FOLR2) in human samples. The Assay Genie human FOLR2 immunoassay is built to quantify this receptor across research samples including human blood fractions and tissue homogenate preparations, with the kit supporting 96 individual determinations per box.

FOLR2, also called folate receptor beta or folate binding protein, is a glycosylphosphatidylinositol-anchored cell surface glycoprotein that mediates high-affinity uptake of reduced folates such as 5-methyltetrahydrofolate. It is most prominently expressed on alternatively activated macrophages and serves as a recognized surface marker of tumor-associated macrophages in several solid tumor types, where it influences folate handling within the immune microenvironment.

Investigators apply this assay to characterize macrophage polarization states, study folate pathway dynamics in inflammatory and tumor microenvironments, and evaluate FRβ-targeted drug delivery strategies relevant to cancer, rheumatoid arthritis, and other autoimmune disease research. The kit provides quantitative protein measurement through pre-coated microplate wells, detection reagents, calibrators, and buffer solutions sufficient to generate a standard curve alongside experimental replicates.