Human FMOD (Fibromodulin) CLIA Kit (HUES01119)

From Assay Genie, this chemiluminescence (CLIA) kit is designed for the precise quantitative measurement of Human FMOD (Fibromodulin) in serum, plasma and other biological fluids, using a sandwich assay format. The assay runs in 4.5h with a sensitivity of 37.50 pg/mL and a detection range of 62.50-4000 pg/mL, and uses a sample volume of 100μL.

Fibromodulin is a key protein involved in extracellular matrix production and organization, with a vital role in tissue development and maintenance. Its dysregulation has been implicated in diseases including arthritis, cardiovascular disorders, and cancer, making it a potential biomarker for disease progression and therapeutic interventions. The assay applies the Sandwich-CLIA principle, with the microplate pre-coated with an antibody specific to Human FMOD.

Validation data show recovery ranges of 88-99% in serum, 95-105% in EDTA plasma, and 87-102% in cell culture media. Reproducibility is reported with both intra-CV and inter-CV below 15%. The kit recognizes Human FMOD with no significant cross-reactivity or interference between Human FMOD and analogues. Synonyms listed include SLRR2E and SLRR2-E. Research Area: Cell Biology.