Human Ficolin 3 (FCN3) ELISA Kit

Ficolin-3, encoded by the FCN3 gene, is a recognition molecule of the lectin complement pathway and an important mediator of innate immunity. This Assay Genie ELISA supports quantitative measurement of human Ficolin-3 in serum-derived specimens, plasma samples, cell culture supernatant, and additional biological matrices, fitting standard in vitro research workflows.

Investigators studying complement-mediated inflammation, infectious disease, autoimmunity, and immune regulation rely on Ficolin-3 quantification as an indicator of lectin pathway activity. Ficolin-3 circulates as a multimeric glycoprotein that recognizes acetylated structures on microbial surfaces, recruiting MASP serine proteases and triggering downstream complement activation. Altered circulating concentrations have been described in studies of rheumatic disease, sepsis, recurrent respiratory infection, and ischemic injury, reinforcing its relevance as a candidate biomarker.

The kit provides reagents sufficient for 96 determinations in a microplate format, with components supplied in individual vials and stabilized for refrigerated storage. Protect from light during use, and aliquot reagents as needed to minimize freeze-thaw cycles.