Human Fibroblast growth factor 23 (FGF23) ELISA Kit

A Sandwich ELISA from Assay Genie intended for the quantitative measurement of Human Fibroblast growth factor 23 (FGF23). The assay is reactive with human samples and is suitable for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Synonyms associated with this target include Phosphatonin, Tumor-derived hypophosphatemia-inducing factor, FGF-23, and HYPF.

Reported performance characteristics include a detection range of 15.6-1000pg/ml and a sensitivity of 10pg/mL. Intra-assay precision is given as 4.6% and inter-assay precision as 6.4%. Recovery has been measured at an average of 84% in serum (range 80-90%) and 86% in plasma (range 80-92%). The assay is specific for natural and recombinant human FGF23.

FGF23 functions as a regulator of phosphate homeostasis, inhibiting renal tubular phosphate transport by reducing SLC34A1 levels, and acts as a regulator of vitamin-D metabolism. The kit falls within the Signal Transduction research area and is intended for research use only.