Human FGF3 (Fibroblast growth factor 3) ELISA KIT (HUFI08182)

The FGF3 (fibroblast growth factor 3) protein is a ~27 kDa member of the heparin-binding FGF family, originally cloned as the INT-2 oncogene and now studied for its role in embryonic patterning, inner ear morphogenesis, and tumor-promoting signaling through FGFR receptors. This Assay Genie kit is supplied as a complete set of reagents packaged for in vitro research use only, intended for laboratories investigating FGF3 concentrations in human-derived samples. Applications include oncology research where FGF3 amplification contributes to aberrant receptor tyrosine kinase activation in squamous and gastric carcinomas, developmental biology studies of otic vesicle formation, and pathway analyses of MAPK cascade signaling downstream of FGF-FGFR binding. The reagents are configured to support quantitative measurement workflows in research settings, with each kit providing calibrated standards, detection antibodies, and assay buffers necessary for the immunoassay procedure. Researchers studying hearing loss genetics, particularly forms associated with chromosome 11q13 alterations, also rely on FGF3 quantification as part of mechanistic investigations of otic development. As with all research-use reagents, the kit components are intended solely for laboratory investigation in a research setting and are not approved for diagnostic or therapeutic applications.