Human Ferrochelatase (FECH) ELISA Kit

Mitochondrial heme biosynthesis research depends on accurate quantification of ferrochelatase (FECH), the terminal enzyme that inserts ferrous iron into protoporphyrin IX. This absorbance-based ELISA from Assay Genie is supplied as a 96-assay kit and is intended for research use only, supporting measurement of human FECH in tissue homogenates and cell lysates. Because reduced FECH activity is associated with erythropoietic protoporphyria and other porphyrias, the kit enables studies of inherited porphyrin disorders, hepatic heme synthesis, and erythroid differentiation. Reagents are provided as a complete set suitable for standard microplate workflows, and the assay can be incorporated into existing plate-reader protocols without specialized equipment. Investigators studying genotype-phenotype relationships, mitochondrial enzyme deficiencies, and dermatological manifestations of protoporphyria can use this product for quantitative analysis of patient and model-system samples.