Human Fc Fragment Of IgA Receptor (FcaR) ELISA Kit

FcaR (CD89) is a 50-70 kDa transmembrane glycoprotein expressed predominantly on myeloid cells, including neutrophils, monocytes, macrophages, and eosinophils. It binds the Fc region of IgA antibodies and triggers effector responses such as phagocytosis, antibody-dependent cellular cytotoxicity (ADCC), and release of inflammatory mediators. Assay Genie's human FcaR ELISA kit provides researchers with a quantitative tool for measuring this receptor across a range of human sample matrices.

Built on a double-antibody ELISA configuration using matched capture and detection antibodies specific to human CD89, the kit produces an absorbance-based readout that can be quantified against a standard curve. Each package supplies reagents sufficient for 96 individual determinations, making it appropriate for medium-throughput studies. Compatible specimen types include plasma samples, serum samples, and tissue homogenates, along with other relevant body fluids encountered in immunological research.

Typical research applications include investigating FcaR involvement in mucosal immunity, IgA nephropathy, autoimmune conditions, and inflammatory disorders, as well as supporting pharmacokinetic studies of IgA-based therapeutics. Reagents are supplied in vials, and components such as lyophilized standards should be reconstituted and handled according to the accompanying protocol insert.