Human FBXO3 ELISA Kit (HUFI07905)

The FBXO3 gene encodes F-box protein 3, a substrate-recognition subunit of the SCF (Skp1-Cullin1-F-box) E3 ubiquitin ligase complex that channels target proteins into the ubiquitin-proteasome degradation pathway. Well-characterised substrates include the PI3K regulatory subunit p85α and the signalling adaptors TRAF1 and TRAF6, linking FBXO3 to PI3K/AKT signalling, innate immune regulation, and inflammatory cytokine output.

This quantitative immunoassay kit is supplied by Assay Genie for measurement of FBXO3 levels across translational research workflows, with reactivity directed at the human protein. Researchers apply it to profile F-box expression in hepatocellular carcinoma, lung adenocarcinoma, and rheumatoid arthritis synovial tissue, and to evaluate small-molecule or genetic perturbations of SCF ligase activity in vitro. Store the unopened kit refrigerated at 4°C and protect the standard and detection antibody vials from light; aliquot reagents to limit freeze-thaw cycles and preserve binding performance across the microplate workflow.