Human FBXO28 ELISA Kit (HUFI04314)

The F-box protein 28 (FBXO28) is a substrate-recognition component of the SCF (Skp1-Cullin-F-box) E3 ubiquitin ligase complex, where it directs the polyubiquitination of target proteins for proteasomal degradation. This kit from Assay Genie provides a quantitative immunoassay for measuring human FBXO28 in research samples, supporting investigations into ubiquitin-proteasome pathway function, oncogenic signaling, and neurodevelopmental disease mechanisms linked to FBXO28 variants.

FBXO28 has been characterized as a regulator of p53 stability and has been implicated in tumorigenic processes including breast cancer cell proliferation and hepatocellular carcinoma progression. Mutations in the FBXO28 gene have been associated with developmental and epileptic encephalopathy (DEE100), making accurate quantification of this protein relevant for oncology, neuroscience, and cell-cycle biology research.

The kit is supplied in a microplate format with all reagents required for the assay workflow. Store the kit refrigerated upon receipt, allow components to equilibrate to room temperature before use, and follow the included protocol for sample preparation and standard curve generation.