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Human FANCI ELISA Kit (HUFI07918)
  • Human FANCI ELISA Kit (HUFI07918)
Assay Genie

Human FANCI ELISA Kit (HUFI07918)

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HUFI07918

Price on request

Description

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FANCI (Fanconi anemia complementation group I) acts with FANCD2 in the ID complex that drives monoubiquitination, chromatin loading, and downstream repair of DNA interstrand crosslinks. This quantitative assay from Assay Genie measures circulating FANCI protein in human serum or plasma-derived specimens using a colorimetric microplate readout across 96 tests per kit. It supports in vitro research into the Fanconi anemia pathway, including studies of bone marrow failure, congenital hematological disorders, and tumor predisposition syndromes linked to defective DNA repair. Investigators working on replication fork stability, genotoxic stress responses, and BRCA1/2 pathway crosstalk can incorporate this kit into cohort screens that compare FANCI abundance between affected individuals and matched controls. Capture antibodies immobilize the target from each specimen while detection antibodies carry the chromogenic reporter; standard curve performance should be confirmed on each run. Reagents require refrigerated storage between uses to preserve antibody activity and conjugate stability. Intended for research use only; not for diagnostic procedures.