Human EXT2 ELISA Kit (HUFI04357)

This quantitative immunoassay from Assay Genie is configured for measuring human Exostosin Glycosyltransferase 2 (EXT2) levels in research samples. The kit supports investigation of the EXT family of glycosyltransferases, which assemble heparan sulfate chains in the Golgi apparatus as a heterooligomeric EXT1/EXT2 complex. Loss-of-function alterations in EXT2 cause type 2 hereditary multiple exostoses, an autosomal dominant skeletal disorder characterized by osteochondroma formation, making EXT2 quantification valuable for studies of bone tumor biology and cartilage development. Researchers probing downstream heparan sulfate-dependent signaling pathways, including Hedgehog, Wnt, and FGF cascades, can use this kit to monitor EXT2 expression across experimental conditions. Each kit is supplied as a complete pack containing pre-coated plates, detection reagents, and a standard curve for quantification, suitable for standard laboratory workflows and stored refrigerated between uses.