Human Exportin 1 (XPO1) ELISA Kit

This quantitative immunoassay from Assay Genie measures human Exportin 1 (XPO1) protein levels in research specimens. XPO1, also called CRM1 (Chromosome Region Maintenance 1), is the principal nuclear export receptor that shuttles proteins and RNA cargo from the nucleus to the cytoplasm, and is a focus of oncology research due to inhibitors such as selinexor, clinically used in multiple myeloma and other hematologic malignancies.

Designed for analysis of human tissue homogenates and cell lysates, the kit supports investigations into nucleocytoplasmic transport, drug response mechanisms, and biomarker validation in cancer cell models. The microplate-based protocol yields an absorbance-based readout on standard laboratory plate readers, simplifying data capture across translational research workflows studying export pathway dysregulation.

Each kit provides reagents for 96 individual determinations. Researchers working on solid tumor drug resistance, leukemic cell biology, or mechanisms of SINE (Selective Inhibitor of Nuclear Export) compounds will find this reagent useful for quantifying endogenous protein in experimental samples, with kit components supplied as single-use vials within the workflow.