Human Exostoses 1 (EXT1) ELISA Kit

Exostosin-1 is a type II transmembrane glycosyltransferase resident in the Golgi apparatus, where it assembles heparan sulfate chains on proteoglycan core proteins. Mutations in the EXT1 gene cause hereditary multiple exostoses, a dominant skeletal disorder marked by cartilage-capped bony outgrowths, while altered EXT1 expression has been documented in sporadic osteochondromas and chondrosarcomas. Reliable quantification of the protein, rather than transcript-only measurements, is therefore valuable in musculoskeletal and tumor biology research.

This Assay Genie ELISA Kit delivers colorimetric readout across 96 assays per kit and is intended for in vitro measurement of human exostosin-1 in tissue homogenates and other sample matrices. Researchers apply kits of this format to probe glycosyltransferase function, heparan sulfate biosynthesis, cartilage and bone tumor pathogenesis, and genetic confirmation workups for hereditary multiple exostoses. The kit is supplied as a complete research-use-only ELISA Kit for laboratory workflows requiring sensitive, plate-based protein detection.