Human EXOSC3 ELISA Kit (HUFI04370)

The EXOSC3 protein (also known as hRrp40) is a core subunit of the RNA exosome complex, essential for 3'-to-5' RNA processing and degradation in eukaryotic cells. This Assay Genie ELISA Kit enables quantitative measurement of EXOSC3 in serum and plasma samples using a human-specific capture antibody, supporting research into neurodegenerative disease pathways such as Pontocerebellar Hypoplasia type 1B (PCH1B), where autosomal recessive EXOSC3 mutations underlie motor neuron and cerebellar atrophy. The kit provides reagents in a microplate format ready for absorbance readout in standard laboratory workflows. Components should be stored refrigerated between uses; the kit is intended for research use only. Useful for biomarker discovery and validation studies in translational neuroscience, with reproducible quantification across experimental replicates for studies of RNA surveillance machinery dysfunction.