Human EXOSC10 ELISA Kit (HUFI04379)

The Assay Genie EXOSC10 ELISA Kit enables quantitative measurement of Exosome Component 10, also known as PM/Scl-100, a catalytic subunit of the nuclear RNA exosome complex involved in 3' to 5' exoribonucleolytic degradation and processing of ribosomal RNAs, snRNAs, and snoRNAs. Researchers studying autoimmune connective tissue disease, particularly polymyositis-scleroderma overlap syndrome where anti-PM/Scl autoantibodies are a diagnostic hallmark, use this assay to measure EXOSC10 protein levels in clinical research samples. The kit is supplied in a microplate format with all reagents required for the immunoassay, and components should be stored refrigerated at 4 degrees C prior to use to preserve antibody binding activity. Reconstituted standards and working detection antibody are stable for short-term use when kept cold; for longer storage, aliquot and freeze at -20 degrees C and limit freeze-thaw cycles to preserve performance. This research-use-only ELISA kit supports translational immunology, biomarker discovery, and studies of RNA quality-control mechanisms in human cells.