Human EXOG ELISA Kit (HUFI04375)

Exonuclease G (EXOG), also termed EndoG, is a mitochondrial nuclease that translocates to the nucleus during caspase-independent apoptosis, where it mediates large-scale DNA fragmentation. This Assay Genie kit provides a 96 Assays format for quantitative measurement of EXOG protein in laboratory samples, supporting studies of programmed cell death, mitochondrial dysfunction, and related pathways implicated in neurodegeneration and oncology. The assay is a useful complement to TUNEL staining, cytochrome c release assays, and caspase activity panels when dissecting intrinsic versus extrinsic apoptotic signaling in cell culture and tissue-derived specimens. Researchers can pair this ELISA with western blot confirmation of EXOG translocation or with qPCR analysis of mitochondrial DNA integrity.