Human ERCC6L ELISA Kit (HUFI04402)

The ERCC6L protein (approximately 140 kDa), also referred to in the literature as PICH (PLK1-interacting checkpoint helicase) or RAD26L, is a member of the SNF2 family of ATPases and plays a central role in chromosome segregation during mitosis, particularly in the resolution of ultrafine anaphase DNA bridges between sister chromatids. Assay Genie supplies a quantitative immunoassay kit built on microplate-based ELISA chemistry, intended for research teams measuring endogenous ERCC6L concentrations in human specimens. The kit is configured for 96 determinations and arrives as a complete research-use-only package, with pre-coated wells, detection reagents, and a standard curve sufficient to interpolate relative protein abundance across prepared lysates.

ERCC6L expression has been investigated in the context of cancer cell proliferation, genomic instability, and spindle assembly checkpoint signaling, and quantitative ELISA measurement can support studies in cell cycle regulation, DNA damage response, and tumor biology research. Reagents should be stored refrigerated and protected from light; allow equilibrated components to reach room temperature before initiating the assay, and avoid repeated freeze-thaw cycles of reconstituted standards to preserve binding activity. The format provides a practical tool for in vitro investigations of mitotic fidelity and chromatin dynamics.