Human ERAP2 (Endoplasmic reticulum aminopeptidase 2) ELISA Kit (HUFI04417)

This quantitative immunoassay from Assay Genie measures endoplasmic reticulum aminopeptidase 2 (ERAP2), an IFN-γ- and TNF-α-inducible zinc metallopeptidase that trims N-terminal residues from precursor peptides in the endoplasmic reticulum and shapes the repertoire of peptides presented on MHC class I molecules. ERAP2 has been linked to autoimmune and inflammatory conditions including ankylosing spondylitis, Behçet's disease, type 1 diabetes, psoriasis, and birdshot chorioretinopathy, where variant haplotypes such as rs2248374 influence disease risk. Researchers studying antigen processing, peptide trimming, and disease-associated ERAP2 expression patterns use this kit to quantify protein levels in human research samples. Each kit is supplied as a 96-Assay format with a pre-coated microplate, matched capture and detection antibodies, standards for curve generation, and assay buffer reagents sufficient for running samples in duplicate. The assay produces a chromogenic readout proportional to ERAP2 concentration, allowing comparison across cell lysates, tissue homogenates, and supernatant fractions from cultured cells. Supports routine immunology, cell biology, and translational biomarker workflows in research laboratories.