Human Equilibrative nucleoside transporter 1 (SLC29A1) ELISA Kit

This Sandwich ELISA from Assay Genie is designed for the accurate quantification of human Equilibrative nucleoside transporter 1 (SLC29A1) in serum, plasma, and cell culture supernatants. The kit uses a colorimetric detection method and is intended for research use only, offering high sensitivity and specificity for reliable and reproducible results.

SLC29A1, also referred to as ENT1 or solute carrier family 29 member 1, is a transmembrane glycoprotein that mediates both the influx and efflux of nucleosides across the cell membrane. It functions as an equilibrative, sodium-independent transporter with higher affinity for adenosine, and is sensitive to inhibition by nitrobenzylmercaptopurine riboside (NBMPR), dipyridamole, and dilazep. Dysregulation of SLC29A1 has been linked to cancer, viral infections, and inflammatory conditions, making it a relevant target for research.

Performance characteristics include a detection range of 0.156–10 ng/mL and a sensitivity of 0.065 ng/mL. Precision is reported with an intra-assay CV of 6.3% and an inter-assay CV of 10.3%. The kit is specific for natural and recombinant human SLC29A1 and is validated for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids.