Human EPRS (glutamyl-prolyl-tRNA synthetase ) ELISA Kit (HUFI04413)

This quantitative immunoassay kit from Assay Genie is configured to measure human glutamyl-prolyl-tRNA synthetase (EPRS), a bifunctional aminoacyl-tRNA synthetase that catalyzes aminoacylation of glutamate and proline onto their cognate tRNAs. EPRS attracts research interest well beyond translation: it participates in the GAIT (gamma-interferon-activated inhibitor of translation) complex that selectively silences inflammatory transcripts in myeloid cells, and a cleaved extracellular fragment of the protein has been reported to act as a cytokine-like signal. Rare loss-of-function variants in EPRS have been linked to hypomyelinating leukodystrophy, broadening the clinical contexts in which circulating EPRS levels are investigated in research settings.

Supplied as a complete kit for research use only, the product supports a standard ELISA workflow with everything required for a quantitative run. Reagent components are shipped refrigerated to preserve binding activity; for working inventory, the kit should be kept refrigerated and protected from light to maintain calibration across repeated runs.