Human Epoxide Hydrolase 1, Microsomal (EPHX1) ELISA Kit

Microsomal epoxide hydrolase is a Phase I biotransformation enzyme anchored to the endoplasmic reticulum of hepatocytes and extrahepatic tissues, where it hydrolyses xenobiotic epoxide intermediates into trans-dihydrodiols. The Assay Genie EPHX1 quantitative immunoassay is used by toxicology, drug metabolism, and population-genetics laboratories to measure this enzyme in human research cohorts, particularly in studies linking common EPHX1 polymorphisms such as Tyr113His and His139Arg to susceptibility to lung, hepatic, and occupational exposure outcomes.

The kit is configured for ninety-six determinations in a microplate format. Reconstituted standards are held at room temperature and protected from light prior to dispensing, and each run is completed within the working stability of the supplied reagents. Researchers commonly pair the readout with genotyping of the Tyr113His and His139Arg variants, or with parallel EPHX1 enzymatic activity assays, to correlate protein abundance with catalytic phenotype across xenobiotic-metabolism studies.

For research use only.