Human Enhancer Of Zeste Homolog 2 (EZH2) ELISA Kit

From Assay Genie, this microplate-based enzyme-linked immunosorbent assay enables quantitative measurement of human Enhancer of Zeste Homolog 2 (EZH2) in tissue homogenates and cell lysates. EZH2 is the catalytic subunit of Polycomb Repressive Complex 2 (PRC2), the methyltransferase complex responsible for depositing trimethylation on histone H3 at lysine 27, a repressive chromatin modification that silences tumor suppressor genes and other developmentally regulated loci. Aberrant EZH2 expression and gain-of-function mutations are documented in prostate carcinoma, diffuse large B-cell lymphoma, follicular lymphoma, and other malignancies, making EZH2 a target of interest for oncology and epigenetics research. The kit is supplied in a 96-assay microplate format with colorimetric readout, providing sufficient reagents for studies in cell culture models and primary tissue extracts. Standard ELISA workflows apply, and laboratories commonly pair this assay with western blot or qPCR validation when characterizing PRC2 pathway activity. Intended for research use only, not for diagnostic or clinical procedures.