Human Endoribonuclease Dicer (DICER1) ELISA Kit

Manufactured by Assay Genie, this sandwich-format assay is designed for the accurate measurement of human Endoribonuclease Dicer (DICER1) levels. It detects natural and recombinant human Endoribonuclease Dicer and is intended for research use only, employing a colorimetric ELISA detection method.

The kit has a reported detection range of 0.312-20 ng/mL and a sensitivity of 0.11 ng/mL. Precision is supported by an intra-assay CV of 5.2% and an inter-assay CV of 8.1%. Linearity has been demonstrated for serum, EDTA plasma, and heparin plasma across dilutions of 1:2, 1:4, 1:8, and 1:16, and recovery is reported at 91-103% for serum and 93-105% for plasma.

Suitable sample types include serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The kit reacts with human samples and the target protein is localised to the cytoplasm, where DICER1 functions as a double-stranded RNA endoribonuclease central to short dsRNA-mediated post-transcriptional gene silencing, microRNA processing, and RNA interference.