Human ELL ELISA Kit (HUFI04451)

Quantify the ELL (Eleven-nineteen Lysine-rich Leukemia) transcription elongation factor in human specimens with this 96 Assays immunoassay kit from Assay Genie. ELL functions as an RNA Polymerase II elongation factor and a core component of the super elongation complex (SEC), where it regulates transcript elongation through chromatin remodeling and histone acetylation activity. Aberrant ELL expression, including the MLL-ELL fusion protein generated by the t(11;19)(q23;p13.1) chromosomal translocation, has been documented in acute myeloid leukemia, making quantitative measurement of ELL valuable for studies of leukemogenesis, transcription regulation, and cancer biology research.

The kit ships as a complete package containing a pre-coated microplate, capture and detection reagents, dilution buffers, wash concentrate, chromogenic substrate, stop solution, and ELL reference standards for standard curve generation. Researchers process samples on standard laboratory plate readers and analyze absorbance readings against the supplied reference. All components should be equilibrated to room temperature before initiating the protocol, and unopened reagents remain stable when held under refrigerated storage conditions.

Supplied for research use only, this product supports laboratory investigation of ELL expression patterns, transcriptional elongation mechanisms, and related oncogenic signaling pathways. The complete protocol, performance validation, and lot-specific quality control data ship with every order, and Assay Genie technical support is available for experimental design, sample preparation, and data interpretation questions.