Human ELAC2 ELISA Kit (HUFI04454)

ELAC2 encodes the zinc phosphodiesterase elaC ribonuclease Z 2, which performs 3' end processing of mitochondrial tRNA precursors. This Assay Genie ELISA kit measures the human ELAC2 protein in human specimens via a quantitative immunoassay. Loss-of-function mutations in ELAC2 cause combined oxidative phosphorylation deficiency 17, a mitochondrial disease characterized by hypertrophic cardiomyopathy and neuronal involvement. Earlier genetic studies also associated ELAC2 variants with hereditary prostate cancer risk, sustaining research interest in the gene across oncology, neurology, and metabolism labs. The kit arrives as a microplate pack with pre-coated capture wells, biotinylated detection antibody, lyophilized recombinant standard, streptavidin-HRP conjugate, wash buffer, TMB substrate, and stop solution. Unopened kit components are refrigerated; equilibrate reagents to room temperature before the run. The capture antibody is human-specific, supporting selective quantification in human-derived samples.