Human EIF2S1 (Eukaryotic translation initiation factor 2 subunit 1) ELISA Kit (HUFI04476)

Translational control under cellular stress depends heavily on the eukaryotic translation initiation factor 2 subunit 1 (EIF2S1), commonly referred to as eIF2α. Phosphorylation of EIF2S1 at serine 51 by PERK, GCN2, HRI, or PKR attenuates bulk translation while permitting selective expression of stress-response genes through the integrated stress response. Laboratories investigating unfolded protein response signaling, viral host-cell interactions, neurodegenerative disease mechanisms, and tumor adaptation to microenvironmental stress routinely measure EIF2S1 abundance in research specimens. This quantitative immunoassay from Assay Genie is supplied as a complete microplate-based kit and is intended for in vitro research use only, supporting studies in cell culture, neuroscience, oncology, and metabolic disease research. The kit provides the pre-coated plate, calibration standards, and detection reagents needed for standard plate-reader workflows in the visible spectrum. EIF2S1 quantification supports both baseline expression studies and experiments probing translational control under chemically or genetically induced stress conditions.