Human EIF2B1 ELISA Kit (HUFI04470)

The EIF2B1 gene encodes the alpha subunit of eukaryotic translation initiation factor 2B, a guanine nucleotide exchange factor required for recycling eIF2-GDP to its active GTP-bound form during protein synthesis initiation. Dysregulation of eIF2B activity is implicated in vanishing white matter disease and integrated stress response pathways, making quantitative measurement of the subunit valuable for translational research.

This Assay Genie ELISA kit is supplied with reagents for 96 individual determinations in a microplate format, intended for research use only. Researchers can apply the assay to human serum or plasma specimens as well as cell culture supernatants and tissue lysates to investigate EIF2B1 expression in neurological, metabolic, and stress-response studies.

Each kit includes a pre-coated plate, standards, detection antibodies, and substrate reagents necessary to perform the assay, with a colorimetric readout compatible with standard laboratory microplate readers. The kit supports both basic discovery research into translation initiation biology and applied biomarker investigations.