Human EFS ELISA Kit (HUFI04490)

Quantify Embryonal Fyn-associated Substrate (EFS) in clinical research samples with this immunoassay from Assay Genie, supplied in a 96 Assays format.

EFS is a cytoplasmic adaptor of the CAS protein family that is phosphorylated by the Src-family kinase Fyn and recruited to integrin and T-cell-receptor signaling complexes, where it regulates cytoskeletal remodeling, cell adhesion, and immune synapse formation.

The kit supports research applications ranging from western blot validation and in vitro cell culture work to flow cytometry companion studies of T-cell activation.

Intended for research use only, it is suited to investigations of EFS expression in hematological malignancies, leukocyte migration, and tumor cell motility, where circulating EFS levels can serve as a marker of Fyn-pathway activity in human specimens.