Human EFNB2 (Ephrin-B2) ELISA Kit (HUFI03383)

The EFNB2 gene encodes Ephrin-B2, a 333 amino acid transmembrane signaling ligand weighing approximately 36 kDa, anchored through a hydrophobic domain and bearing a cytoplasmic PDZ-binding motif that mediates reverse signaling into the ligand-expressing cell. This Assay Genie quantitative immunoassay supports vascular biology and oncology workflows where EFNB2 serves as a biomarker of arterial identity, endothelial remodeling, and tumor neovascularization. The pre-coated microplate reagents bind selectively the human Ephrin-B2 extracellular domain, and validation studies report no significant cross-reactivity with the closely related ephrin-B1 paralog under standard conditions, making the kit appropriate for measuring endogenous ligand levels in clinical and translational studies of angiogenesis, hepatocellular carcinoma progression, and neurovascular patterning.