Human Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) ELISA Kit

This Sandwich ELISA from Assay Genie is designed for the quantitative measurement of human Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. The kit detects natural and recombinant human ENTPD5 with a detection range of 0.78-50ng/mL and a sensitivity of 0.404ng/mL, and is described by the manufacturer as a powerful tool for accurately measuring ENTPD5 levels in human biological samples, providing precise and reliable results for research purposes.

ENTPD5 is a uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis supports protein N-glycosylation and folding in the endoplasmic reticulum, and the enzyme plays a role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling. The protein is found in the endoplasmic reticulum and is also secreted, and is highlighted by the manufacturer for use in cancer research. The UniProt entry is O75356, with a listed molecular weight of 47,517 Da. Synonyms include CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, Nucleoside diphosphatase, Uridine-diphosphatase ENTPD5, GDPase ENTPD5, UDPase ENTPD5, NTPDase 5, CD39L4, and PCPH. The product is intended for research use only.