Human ECE2 ELISA Kit (HUFI04519)

Endothelin-Converting Enzyme 2 (ECE2) is a zinc-dependent metalloprotease that processes big endothelin-1, big endothelin-2, and big endothelin-3 into their vasoactive mature forms, contributing to vascular tone regulation and neuropeptide signaling. Assay Genie supplies a quantitative immunoassay kit for measuring ECE2 levels in human research samples, supporting cardiovascular, neurological, and developmental biology studies.

This in vitro kit is configured for 96 Assays per box and is intended for research use only. Reagents are shipped refrigerated and should be stored according to the enclosed protocol to maintain stability throughout the workflow. The immunoassay can be applied to a range of human-derived matrices, supporting laboratory investigations of endothelin pathway dysregulation in hypertension research, neurodegeneration models, and endothelial function studies.

ECE2 shares functional overlap with ECE1 but is preferentially expressed in neural tissues and certain endothelial populations, making it a relevant target for studies of central nervous system peptide processing, including the conversion of big endothelin and certain opioid peptide precursors. The kit supplies the pre-coated plate, detection reagents, standards, and assay buffer required to perform the complete protocol, providing a practical tool for biochemistry, pharmacology, and molecular biology laboratories focused on human endothelin biology.