Human Early Endosome Antigen 1 (EEA1) ELISA Kit

The Early Endosome Antigen 1 (EEA1) protein is a 162 kDa peripheral membrane protein that serves as a key marker of early endosomal compartments in mammalian cells. It contains a FYVE zinc finger domain that specifically binds phosphatidylinositol 3-phosphate, anchoring the protein to early endosome membranes where it regulates vesicle tethering and fusion through interactions with Rab5-GTP and SNARE complexes. This kit from Assay Genie supports quantitative measurement of EEA1 levels in cell lysates and tissue homogenates, with reactivity validated against human, mouse, and rat EEA1 isoforms for research applications including studies of endocytic trafficking, receptor internalization, autophagy, and membrane dynamics. The microplate-based format enables processing of up to 96 samples in a single run with refrigerated storage of reagents to preserve antibody activity. Intended for research use only, in vitro applications.