Human E1A Binding Protein P300 (EP300) ELISA Kit

EP300 (E1A Binding Protein P300) is a histone acetyltransferase and transcriptional coactivator, and this research-use ELISA Kit from Assay Genie provides quantitative measurement of EP300 in human tissue homogenates and cell lysates. As a chromatin-modifying enzyme, EP300 acetylates histone and non-histone substrates and serves as a cofactor for p53, NF-κB, and multiple nuclear receptors, linking it to cell cycle control, differentiation, and tumor suppression pathways. Mutations in the EP300 gene are associated with Rubinstein-Taybi syndrome and have been reported in a range of cancers, making reliable quantification of EP300 protein valuable for disease mechanism and biomarker studies.

The kit is supplied in a 96 assays format and includes a precoated microplate, calibration standards, detection reagents, and substrate. Absorbance is read on a standard microplate reader, and EP300 concentrations in experimental samples are interpolated from the standard curve. Each pack is a complete kit intended for laboratory research applications in cancer biology, epigenetics, and signal transduction studies.