Human Dystrobrevin Beta (DTNb) ELISA Kit

This quantitative immunoassay kit from Assay Genie enables measurement of human Dystrobrevin Beta (DTNb) protein in tissue homogenate preparations. DTNb is a cytoplasmic component of the dystrophin-associated protein complex (DAPC), where it links dystrophin to syntrophin and contributes to cytoskeletal scaffolding at the neuromuscular junction and in polarized epithelial cells. The protein has been investigated in studies of Duchenne muscular dystrophy pathology, neuronal signaling related to schizophrenia, and renal epithelial DAPC composition.

The kit is supplied as a complete reagent set, sufficient for 96 individual determinations in a microplate format, with an absorbance-based readout on a standard plate reader. Components include a pre-coated microplate, calibrator standards, biotinylated detection reagent, enzyme conjugate, wash buffer, substrate, and stop solution. Researchers studying dystrophinopathy mechanisms, neuromuscular junction organization, or comparative expression profiling across patient cohorts can apply this kit to normalize DTNb abundance in muscle biopsy lysates, kidney tissue homogenates, or brain preparations.

All reagents should be kept refrigerated upon arrival to preserve antibody binding activity, and the kit is intended for research use only. Prepared working solutions should be aliquoted to limit repeated freeze-thaw cycles. The reagent set supports DAPC biology investigations in which DTNb expression is tracked across control and disease tissue samples, treatment-response time courses, and genotype-phenotype correlation studies.