Human Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1) ELISA Kit

The DYNC1H1 ELISA kit from Assay Genie enables quantitative measurement of human cytoplasmic dynein 1 heavy chain in tissue homogenates and biospecimens. The target protein is the catalytic subunit (~532 kDa) responsible for microtubule-based retrograde transport of organelles, signaling complexes, and mRNA granules along axonal microtubules. Investigators in neurobiology and neuromuscular research apply this assay to examine DYNC1H1 expression in cellular and animal models of Charcot-Marie-Tooth disease type 2O, SMA-LED (spinal muscular atrophy with lower extremity predominance), and autosomal dominant intellectual disability, all of which have been linked to DYNC1H1 mutations.

The immunoassay runs on a standard microplate with an absorbance readout on a conventional plate reader. Each kit supplies reagents sufficient for 96 determinations. Reconstituted standards and prepared samples are handled at room temperature prior to loading.

For research use only. Not intended for diagnostic procedures.