Human Dual Specificity Phosphatase 6 (DUSP6) ELISA Kit

The DUSP6 gene encodes a dual-specificity phosphatase that selectively dephosphorylates ERK1/2 within the RAS-RAF-MEK-ERK signaling cascade, acting as a feedback brake on MAPK output. Altered DUSP6 expression is reported in colorectal, pancreatic, and lung cancers, supporting its use as a biomarker and pathway-activity readout in tumor biology.

This Assay Genie kit supports quantitative measurement of human DUSP6 protein in cell lysates and tissue homogenates. Researchers profiling MAPK pathway activity, screening kinase-pathway inhibitors, or comparing phosphatase levels between patient-derived samples can integrate the readout with Western blot analysis of phosphorylated ERK.

The microplate kit ships with reagents sufficient for 96 assays. Reconstituted standards and the detection antibody should be refrigerated upon receipt and aliquoted to limit repeated freeze-thaw cycles; protect the conjugate from light. For in vitro research use only — not for diagnostic procedures.