Human DNER (Delta and Notch-like epidermal growth factor-related receptor) ELISA KIT (HUFI05317)

DNER (Delta/Notch-like EGF repeat-containing transmembrane protein) is a type I transmembrane glycoprotein bearing multiple EGF-like extracellular repeats that functions as an activating ligand for Notch receptors. It is prominently expressed in cerebellar Purkinje neurons and has been linked to astrocyte differentiation, gliogenesis, and modulation of the tumor microenvironment in glioblastoma, breast carcinoma, and hepatocellular carcinoma research.

This quantitative kit from Assay Genie enables measurement of soluble DNER concentrations in research samples, supporting investigations into Notch signaling, neuronal development, and oncology biomarker discovery. The workflow uses a pre-coated microplate, biotinylated detection antibody, recombinant standards, and streptavidin-HRP reagents to deliver a complete immunodetection protocol. Reagents are intended for research use only, should be refrigerated at 4°C, protected from light, and remain stable through limited freeze-thaw cycles once reconstituted.