Human DNASE2 (Deoxyribonuclease-2-alpha) ELISA Kit (HUFI03469)

Lysosomal acid endonuclease DNASE2 (Deoxyribonuclease-2-alpha) is essential for degrading chromosomal DNA from apoptotic cells and from erythroid precursors that enucleate during red blood cell maturation. This ELISA kit from Assay Genie provides a quantitative immunoassay for human DNASE2 protein, supporting studies of innate immunity, autoinflammatory disease, and erythropoiesis.

The 96 Assays microplate format allows researchers to process multiple samples in parallel. The kit uses an absorbance-based readout compatible with standard laboratory plate readers. Each kit includes pre-coated plates, detection reagents, and standards needed to generate a standard curve for interpolating unknown sample concentrations.

DNASE2 deficiency has been linked to type I interferon-driven autoinflammation in murine models, and altered expression has been reported in human autoimmune conditions. Scientists studying apoptotic DNA clearance, lysosomal function, and immune regulation use this assay to quantify DNASE2 levels in their samples.

The kit is intended for in vitro research use only, supporting investigations in cell biology, immunology, and hematology research laboratories.