Human DNA Methyltransferase 3A (DNMT3A) ELISA Kit

Accurate quantification of human DNMT3A protein supports research into epigenetic regulation, X-chromosome inactivation, and genomic imprinting. This de novo DNA methyltransferase catalyzes methylation at CpG dinucleotides and is linked to acute myeloid leukemia, Tatton-Brown-Rahman syndrome, and clonal hematopoiesis, so reliable immunoassay tools are valuable for oncology, developmental biology, and epigenetics laboratories.

This Assay Genie kit provides all reagents required to perform the immunoassay in 96 determinations, with components supplied in vials and bottles ready for use with a standard microplate-format workflow. It is intended for research use only and is validated for human cell lysates and tissue homogenates, making it appropriate for comparing DNMT3A expression across primary biopsies, cultured cell lines, and xenograft material.

Common applications include monitoring DNMT3A abundance following siRNA knockdown or CRISPR editing, screening chemical libraries for modulators of methylation capacity, and profiling enzyme levels in leukemia versus normal hematopoietic controls. Store the kit refrigerated and protect from light to preserve reagent integrity throughout the shelf life of the kit.