Human DNA Methyltransferase 1 (DNMT1) ELISA Kit

DNMT1 is the principal maintenance methyltransferase that propagates 5-methylcytosine patterns across daughter strands during DNA replication, making quantitative measurement of its protein abundance essential for epigenetic studies. This quantitative immunoassay from Assay Genie is configured to measure human DNMT1 in tissue homogenates and cell lysates using a colorimetric readout, and the kit ships with materials sufficient for 96 individual determinations in a microplate format.

Researchers apply the assay to investigate aberrant methylation in cancer cell lines, track DNMT1 expression during differentiation protocols, monitor enzyme levels in disease models where methylation homeostasis is disrupted, and characterize responses to epigenetic drugs that target methyltransferase activity. The kit is intended for research use only; samples should be handled at appropriate temperatures, and unused reagents are refrigerated to preserve antibody activity until the expiration date.