Human DNA Damage Inducible Transcript 3 (DDIT3) ELISA Kit

Quantitative measurement of DNA Damage Inducible Transcript 3 (DDIT3), the ER stress-responsive transcription factor also referred to as CHOP or GADD153, supports investigations into unfolded protein response signaling and apoptosis induction in human cellular models. This Assay Genie ELISA Kit is configured for microplate format and is reactive against human samples, including tissue homogenates and cell lysates obtained from cultured lines or primary tissue.

DDIT3 expression is widely used as a downstream indicator of PERK pathway activation during prolonged endoplasmic reticulum stress, making this reagent applicable to research on neurodegeneration, metabolic disease models, ischemic injury, and tumor cell survival mechanisms. The kit is intended for research use only and provides a colorimetric workflow compatible with standard plate readers. Each kit contains reagents sufficient for 96 individual determinations, allowing screening of multiple experimental conditions, time points, or treatment groups within a single experiment.