Human Dkk-4 PharmaGenie ELISA Kit (SBRS0499)

The Human Dkk-4 PharmaGenie ELISA Kit from Assay Genie is configured for quantitative profiling of Dickkopf-4, a secreted Wnt/β-catenin pathway antagonist, with reactivity specific to the human Dkk-4 isoform. Dkk-4 competes with Wnt ligands for LRP5/6 co-receptor engagement, modulating β-catenin–dependent transcription in contexts ranging from embryonic patterning to tumor progression. Researchers investigating lung adenocarcinoma, hepatocellular carcinoma, and breast carcinoma biology, as well as bone metabolism and reproductive tissue development, commonly employ this kit to interrogate Dkk-4 expression dynamics. Reconstituted standard should be frozen in aliquots, and the microplate components are intended for research use only workflows. Each kit includes a pre-coated 96-assay microplate, biotinylated detection reagent, streptavidin-HRP conjugate, wash buffer, and substrate solution to support absorbance-based quantification in standard laboratory incubators and plate readers.